INNOVATION GALLERY

Aidaptus® is a disposable auto-injector platform which provides versatility for pharmaceutical companies and intuitive medication delivery for patients' self-treatment. Aidaptus can be used with both 1mL and 2.25mL ISO syringes (cropped and small round flange) in the same base device with minimal change parts, it is also designed to work with a range of fill volumes. This minimises the level of validation testing and regulatory requirements when selecting a device for each drug and formulation. It provides flexibility for pharmaceutical companies during the clinical trial phase of drug development and for life cycle management when varying formulations may be required.

The multisert is a combination and assembly of two up to six different leaflets – simple or complex leaflets, as well as patient cards, from same or various sizes – through bands, stickers or glue dots. This complex construction is a solution to keep a compact and condensed leaflet in the folding carton, despite a growing quantity of information to mention. It particularly enables patients and caregivers to quickly get right and accurate medical information for critical pharmaceuticals to avoid any drug misuse.

West’s new 4040 LyoTec® Westar® Select Lyophilization Stoppers use a state-of the-art elastomer formulation (4040/40) developed with multi-dimensional elastomer expertise and a Quality-by-Design (QbD) development approach. These lyophilization stoppers meet a broad range of requirements to protect drug quality and compatibility including ultra-low extractables and leachables, low moisture content, a low level of particulates, and low fragmentation and coring. The 4040 LyoTec components provide drug manufacturers with confidence in a high-performing packaging product that will aid in de-risking their drug from development through patient administration. The LyoTec stopper designs with B2-coating are available in 13mm and 20mm igloo configurations proven to work across ISO glass vials of various blowback geometries, thus delivering high functionality and reliability. The new formulation features low particulates through our validated Westar® Select wash process and FluroTec® film on the flange prevents sticking to lyo shelves. LyoTec®, FluroTec® and Westar® are registered trademarks of West Pharmaceutical Services, Inc., in the United States and other jurisdictions. FluroTec® and B2-coating technologies are licensed from Daikyo Seiko, Ltd.

YpsoMate On is the world’s first pre-filled autoinjector with integrated connectivity that automatically logs injections on the user’s therapy management app. This new autoinjector adds connectivity but retains the market-proven 2-step handling of the YpsoMate autoinjector platform. YpsoMate On includes an advanced Bluetooth proximity measurement protocol which automatically connects the injection device and the smartphone. This simplifies the user journey by removing the need for pairing. The injection data is automatically transferred to the user's therapy management app and the associated cloud. As such, YpsoMate On provides connectivity without compromising ease-of-use.

Sween aims to make the act of self-injection of medication by patients using injection pens easier, more serene, and safer. The device mechanically helps patient to insert needle inside skin at correct depth before injection and to reduce his/her fear during the whole injection process. It should then be used by first time user and regular user uncomfortable with needle insertion. Needle phobia affects 5 to 9% of patients and 30% of people is refractory to needles(1). This device can be re-used for the next injections and with the next injection pens. (1) sources - Craske, Antony, & Barlow, 1997; Kleinknecht, 1987; Mark, 1988

InsulCheck® DOSE by Innovation Zed, designed in collaboration with SHL Medical, is a reusable pen injector add-on that uses Bluetooth® technology to automatically transfer injection time and number of dose units dialed to a mobile application. InsulCheck DOSE is designed to be compatible with market-ready insulin pens or those under development through a customizable sleeve that can be tailored for different pens. Its proprietary multi-sensor technology enables detection of units dialed. A built-in firmware over-the-air (FOTA) capability further enables continuous optimization of the device’s firmware even after deployment, therefore allowing InsulCheck DOSE to continually improve its device performance.

Eitan Insights™ is a cloud-based platform, providing clinicians and homecare providers full remote visibility of Eitan Medical’s suite of advanced infusion and drug delivery devices, which include the Sapphire™ infusion pump platform, Avoset™, a connected infusion system for the homecare market, and Sorrel™ a wearable drug delivery platform designed for on-body subcutaneous injections. Eitan Insights empowers healthcare providers to offer a wide range of therapies in the comfort of patients’ homes. The Insights system aggregates treatment data, providing caregivers with near real-time analytics, and offers homecare providers remote access to their pump fleet, paving the path for improved operational efficiency.

Our product is the “IoT Pixel”: a battery-free Bluetooth enabled smart label that powers itself by harvesting RF energy. By sticking a pixel onto plastic crates, pharmaceuticals, and packaging, they are instantly connected to the IoT; giving them constant connectivity, sensing, and visibility. This added intelligence will change the way they are made, distributed, sold, used, reused, and recycled.

RayDyLyo® TearCap is the latest innovation in the RayDyLyo® range. A plastic Total Tear Off Cap for Ø 20 mm vials that eliminates the crimping operation and allows an easy access to the stopper after cap removal. Tear Off caps are recommended for mixing and reconstituting product, and for all applications that requires the complete removability of the cap to access the content. RayDyLyo® TearCap is are made of 2 different plastic raw materials to facilitate cap removal and secure the breakable section on the body part. RayDyLyo® TearCap is more ergonomic with reduced opening efforts and no sharp edges.

Aclar® barrier films and Aclar Edge™ bottles protect medicines that improve the lives of individuals throughout the globe by providing the moisture barrier protection needed for drug stability and patient safety. Tried and trusted throughout the pharma industry, Honeywell has continued to innovate to meet the ever-growing needs of customers. One example of this is through our sustainability efforts. The Aclar® portfolio carbon footprint has improved by over 50% since 2012 and Aclar® films contain up to 25% virgin reclaim material from our production process. Recently, TerraCycle® has determined that Aclar Edge™ achieves technical recyclability.

This pioneering connected drug-delivery device with mobile app from Aptar Pharma, is the first digital healthcare solution of its kind to improve adherence and compliance for patients undergoing Stallergenes Greer’s Allergen Immunotherapy treatment (AIT) with sublingual solutions. The base-mounted sleeve of the connected device attaches seamlessly and discreetly to the primary packaging (a glass vial and dropper actuator). The integrated sensing and feedback elements then record data on self-administration events, informing the patient to non-compliance. All data is transferred via Bluetooth® to the app, which can be configured to issue alerts and reminders to support ongoing adherence and, ultimately, improve patient outcomes.

Aptar Pharma’s PremiumCoat® platform comprises an end-to-end package of products, data and services for containing and protecting sensitive drug formulations in vials or pre-filled syringes (PFS). PremiumCoat® ETFE film-coated Bromobutyl closure solutions include stoppers for 13mm/20mm vials, plungers for 1mlL PFS, and soon-to-be-released plungers for 1-3mL PFS. Combining the expertise of Aptar Pharma’s companies, we have developed a series of advanced evaluation protocols to test and demonstrate PremiumCoat®’s performance. PremiumCoat® products can be supplied with critical technical data contained in the Data Package or as part of an integrated Service Package to support the de-risking and accelerating the development of drug products

Sycare secure is a tamper proof system for pre-filled syringes. The cap cannot be unscrewed without breaking the tamper-evident system, even if using special tools or equipment. Sycare Secure ensures that the product in the barrel remains intact. In addition, thanks to Sycare's innovative design, the tamper-evident system remains within the overall dimensions of the barrel. This eliminates the need to change the secondary packaging and makes the system aesthetically pleasing. The threaded cap’s two large parallel faces allows doctors to unscrew it easily, even when wearing gloves.

Grass fibre production takes place purely mechanically without chemical preparation, causes up to 95 percent less CO2 emissions, requires hardly any precious water and only a little energy compared to virgin fibre pulp obtained from wood. Depending on the product, up to 30 percent of the pulp from wood can be replaced by grass fiber, with the same functionality and quality. Made from renewable raw materials, grass paper is 100 percent recyclable and can be disposed of like waste paper. As an environmentally friendly alternative to traditional cardboard, grass paper is therefore very much trending and stands out for its natural look and the tactile feel of the natural fiber material.

Neutroplast, in collaboration with PIEP, has produced pharma grade jars of two biopolymers. Two combinations were tried i. Polypropylene and eucalyptus nitens; ii. High density polyethylene and mussel shells. This is a solution that promises to innovate the market while reducing plastic consumption. These packages are complemented by the DOSEA+ device. It has been developed within the DOSEA Smart Label project, by Neutroplast, Beyondevices and CeNTI, as a simple and eficient solution that promises to alert, control and manage medication taking both at professional and household levels. Due to its characteristics, the device can be applied in all types of treatment that requires strict control.