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24 & 25 January 2024
Paris Expo, Porte de Versailles - Hall 7.2 | Paris, France
Showcasing all exhibitor innovations that were submitted for the Pharmapack Awards, the Innovation Gallery gives a great overview of recently launched products. From anti‑counterfeiting and track and trace solutions, to patient adherence and dosage forms, these products represent the ever evolving pharmaceutical packaging and drug delivery industry.
High-Dose/High-Volume subcutaneous (SC) drug delivery requires dedicated delivery technology to enable patient-centric and effective drug administration. The trend towards such high-volume delivery via the SC route is increasing and the Sonceboz OBI-Platform is the answer to many unresolved challenges in drug delivery such as proper feedback, tolerability, system flexibility.
UniSafe® reusable connected auto-injector is a companion device for UniSafe 1mL safety syringes designed for delivery of subcutaneous medication. The mechanical function ensures the device is always ready for use as it does not rely on batteries or chargers to deliver the medication.
With a continual dose progression indicator and true end of dose notification the auto-injector guides patients during their drug administration. UniSafe Auto-injector has the option of added connectivity for data exchange between patients and healthcare providers helping to track therapy compliance. Data is automatically transferred via Bluetooth® when the injection commences therefore no docking stations are required.
Symbioze® is specifically tailored to administer complex drugs, such as biologic therapies, thanks to a highly engineered, reliable drug delivery system.It is suitable for various drug platform and compatible with market-proven cartridges, as well as standard manufacturing process. The cartridge is prefilled and preloaded in the disposable part for patient safety and ready-to-use feature. It accommodates large volumes such as 20ml and beyond, while preserving the formulation integrity - which is critical especially with monoclonal antibodies. It is designed to reconcile complex drugs injection with stakeholders’ (patients, HCP or payers) most demanding needs, with enough flexibility for adjustment to any pathology, targeted patient population and drug posology with different volumes, flowrates, and viscosities. Its reusable core technology can be re-used across multiple injections, leveraging its sustainable benefit for pharmaceutical players. It also includes connectivity features, to improve patients’ adherence and compliance. To foster patient injection experience, our on-body injector offers a safe and reliable injection thanks to the state-of-the-art engineering, including automatic soft canula insertion and needle retraction.
Digi-Cap is the companion closure for clinical studies and phase 1 & 2 trials. The 38 mm Child-resistant closure use patient behaviour data to Improve medication adherence. The Smart cap records temperature STORAGE levels and registers history log.With our smart closure use data to improve trial efficiency, medication effectiveness, and patience adherence by electronically monitoring patient therapy compliance.
-Improve Trial efficiency:
Use behavioural data to support trial results and conclusionso -Optimize Medication effectiveness
Data can also be used to finetune when medication should be taking at specific times of the day to maximize its effectivenesso
-Increase Patience adherence
Act as a reminder to patient to take the medication on time and to properly store medication.
Suited for Clinical trials, research studies, drug development trials, academic purposes.
The Congruence Autoinjector is a next generation disposable autoinjector platform, designed for self-injection applications including high-dose drugs. It leverages a proprietary compressed-gas power source and has significant advantages over currently available legacy devices, including the ability to deliver higher viscosity (100+cP) / larger volume drugs (2mL+) with enhanced usability and easier customization – all in a compact format, with standard primary containers incorporated. In addition, the Congruence Autoinjector includes novel usability features to mitigate well-known autoinjector user errors, such Injection Pause™ technology and a Visual Dose Progress Indicator to address premature removal from the skin prior to end of dose.
Eitan Insights™ is a cloud-based platform, providing clinicians and homecare providers remote visibility of treatment date from Eitan Medical’s suite of advanced infusion and drug delivery devices, which include the Sapphire™ infusion pump platform, Avoset™*, a connected infusion system for the homecare market, and Sorrel™ a wearable drug delivery platform designed for on-body subcutaneous injections. Eitan Insights™ empowers healthcare providers to confidently provide infusion and drug delivery therapies from the comfort of the patient’s home.
*Avoset is not for sale, pending regulatory approval/clearance. Specifications are subject to change.
Stevanato Group's On-Body Delivery System is being developed in collaboration with Bexson Biomedical Inc. – an early-stage US-based biopharmaceutical company – for the subcutaneous treatment of moderate-to-severe acute post-operative pain. The therapy is based on a new formulation of a controlled substance (ketamine), providing an alternative to highly addictive and easily misused opioids. By combining this new therapy with a state-of-the-art On-Body Delivery System, patients will be able to self-administer controlled doses of pain medication at home. The device is composed of a disposable pod with a pre-filled and pre-loaded 3mL cartridge and a controller which is reusable up to 10 times.
RS01X is a digital Capsule based Dry Powder Inhaler with built-in sensors and digital services. Used mainly for the control and treatment of any lung disease or any systemic disease for which inhalation is the chosen route of delivery. The new RS01X™ tracks inhaler use and connects to a companion app which provides personalized guidance to improve adherence and inhaler technique. RS01X is integrated with Amiko’s Respiro™, a digital medicine platform for use with connected inhalers that combines data, artificial intelligence (AI), and elegant digital experiences to upgrade respiratory care.
EVEON New formulations such as gels, highly‐viscous products, suspensions, emulsions are challenging to prepare both for patients and healthcare professionals.According to your needs, EVEON offers a flexible solution : Intuity® Mix. Based system using PFS, syringe or cartridge as primary containers, Intuity® Mix is a fully automated device technology platform for the automatic preparation of drugs.
• Not user dependent
• Reliability of the process
• Custom device
• Easy to use
• Reallocate healthcare practitioner time to more added value steps
Applications areas: gels, highly‐viscous products, suspensions, emulsions
Covid has changed the world. Not only in dealing with the pandemic and digitalization, but also in relation to our own health security. Rapid Covid tests have become indispensable in day-to-day business. In order to be able to act quickly, millions of quick tests were manufactured and made of plastic. We thought one step ahead and developed a quick test completely without plastic- i.e. made of recyclable cardboard mono material.
Polyfoil® Mono-Material Barrier tube (MMB) is a high-performance tube, offering superior protection to pharma formulas and is recyclable! Due to the application of innovative oriented and combined barrier technologies as well as pharma grade contact layers, the tubes provide excellent product compatibility and maintain premium product protection while keeping the known aesthetic characteristics of Neopac's conventional Polyfoil® tubes.Combined with HDPE screw and hinge closures, the tube is ready for recycling in the PE rigid streams.
The incorrect administration of medication can have unpleasant consequences for the patient. This is particularly the case with self-application medicines. Our printed sensor helps to improve the user-friendliness of your refrigerated medication. If the medication is still too cool, it is often painful to apply. In addition, the effectiveness of the medication could be delayed by the wrong viscosity. The label is equipped with sensor technology that turns blue when it is stored below eight degrees Celsius. As soon as the temperature warms above 18 degrees Celsius, the sensor changes color and an 'OK' message is displayed on the label.
APF futurity, the first-to-market recyclable nasal spray pump from Aptar Pharma - this device is the first metal-free nasal spray pump, made from only polyolefin without any disrupting materials. APF futurity achieved a "highly recyclable rate" by the cyclos-HTP institute (November 2022) when associated to a HDPE container. Based on Aptar Pharma's Tip-Seal technology for preservative-free formulations and applicable for nasal saline or comparable compounds, this nasal spray enables direct and easy recycling for the consumer, when empty after use. It minimizes separation efforts in recycling streams, supports higher quality of recyclates and reduces the CO2 footprint of nasal spray products without causing trade-off on performance and safety. The APF futurity has been assessed with Aptar's Eco-design tool to ensure the recyclable nasal spray pump fulfils state of the art sustainability requirements.
New IDC®: Integrated Desiccant closure, developed by Airnov is the latest innovation in our range of desiccant closures.This unique design closure will be adaptable on SP 400 bottles, while including a child-resistant system and a tamper-evident disk on the top. New IDC is designed to help the pharmaceutical, nutraceutical or diagnostic companies to remove several operation steps on their filling lines. Indeed, with IDC, no desiccant needs to be dropped and no induction seal operation is required online.By reducing components, inventory and manufacturing steps on filling lines, this new closure: IDC contributes to improve the environmental approach.
Our Pulpable label is a plastic-free, water-soluble adhesive label with a water-dispersible adhesive (TAPPI UM213 standard).Our label is very innovative because it uses a film made of natural polymer granules 100% biosourced and biodegradable.Our adhesive is water dispersible, which is an essential asset for the recycling of cardboard. We realize a digital printing on HP press with anti-counterfeit printing techniques very efficient for the health market.
BD EffivaxTM Glass Prefillable Syringe, the next generation vaccine syringe, will further help customers meet the stringent demands of today’s vaccine manufacturing through design enhancements focused on fill/finish and container reliability. Through improved quality specifications, BD EffivaxTM is designed to reduce the risk of line stoppage and improve the total cost of ownership, manufacturing capacity and supply availability.
The Daikyo Crystal Zenith® (CZ) 2.25mL insert needle is a break-resistant, polymer syringe of choice to protect larger volume sensitive molecules during self-administration. For drug developers wishing to avoid glass, this syringe system protects delicate molecules as there is no silicone oil added for functionality, no lubricants, tungsten, or glue, making it a low-risk solution to the challenges of particles, interactions, and protein aggregation. Their break-resistance also reduces concern of injection malfunctions during high force, large volume injections.
Aptar Pharma’s AdhereIT® platform addresses patient adherence to self-injected medication by supporting patients with initial onboarding and ongoing adherence to their therapeutic treatments. The two design options - AdhereIT® 360 Base and AdhereIT® 360 Clip integrate with self-injection devices, providing visual, audio and haptic feedback during the injection process for accurate dosing. Encrypted data is transferred to the AdhereIT® smartphone app via Bluetooth® which incorporates complementary resources for patients including training videos, injection reminders and drug re-order notifications. Data can be shared with HCPs to track patient performance through a dashboard, providing accurate data to support ongoing therapeutic programs.
SCHOTT TOPPAC® - A polymer PFS for low temperatures
As the COVID pandemic is transitioning to an endemic level, periodic booster shots, similar to the flu, could improve protection significantly. Here a single-dose package can support HCPs by providing a safe and easy-to-administer solution allowing for more efficiency, less drug waste, and fewer medical errors. SCHOTT TOPPAC® 1ml long is a preferred solution for required extremely low temperatures down to -80°C. A comprehensive data package shows superior performance of the entire syringe system: container closure integrity, break-loose and gliding forces, plunger movement, sub-visible particles, and LNP (lipid nanoparticles) stability.
Leveraging our market-leading EZ-fill® technology, Stevanato Group developed EZ-fill Smart™: an enhanced version of our pre-sterilized platform aiming to make RTU vials a standard, ultimately increasing patient safety. The secondary packaging is redesigned to yield a significant reduction of contamination risks during customers operations. This optimized platform features no glass-to-glass and no glass-to-metal contact process which improves quality and integrity of the vials throughout the product life cycle. By using biopolymers and reusable material for the packaging, EZ-fill Smart Nest & Tub is a more sustainable solution for the industry.
Datwyler’s 5/8 in. RNS is designed with a best-in-class rubber formulation known as FM30. FM30 enables a worldwide regulatory compliant with a low extractable profile and an adequate gas permeability that allows ETO sterilization and facilitates controlled pull-off force, high separation force and excellent seal integrity. The design is also compatible with standard PFS and runs on standard syringe assembly lines with no necessary changes.
Through a strategic partnership with Corning, one of the world’s leaders in glass science, West is redefining the future of containment solutions by creating a truly integrated system that will help de-risk customers’ drug development and manufacturing processes by providing comprehensive product information in one DMF and end-to-end support. West is pleased to present our first offering from the partnership with the introduction of Ready Pack with Corning’s Valor® RTU Vials with SG EZ-fill Technology, a revolutionary new pharmaceutical glass packaging technology. Valor RTU Vials with SG EZ-fill Technology pharmaceutical packaging helps to enhance the storage and delivery of drugs, provide more reliable access to medicines essential to public health, and optimize production efficiency. This purpose-built pharmaceutical glass is specifically designed to address the challenges of today’s manufacturing operations.
The PACKSYS ampoule dispenser is a multifunctional dispensing system for glass ampoules. It guarantees a clean breaking of the ampoules and an easy and hygienic application of the product. Due to its standard thread, it can be used with a variety of applicators, such as spray pumps, roll-ons or dap applicators.Empty ampoules can easily be replaced by taking off the bottom part. The device also works as a container for open ampoules – protecting the content from spilling or contamination.
The advent of the modern autoinjector made it possible to self-administer 1 mL drugs with a patient-friendly device that is supported by a well-defined regulatory pathway and a reasonable development cost. Paving the way for large-volume/high-dose autoinjector combination product development meant that we needed to challenge the status quo, resulting in Maggie 5.0 – an innovative, large-volume, cartridge-based autoinjector built with SHL’s market-proven Needle Isolation Technology (NIT®). A two-step autoinjector that features a customizable cannula, it was developed with a focus on opening new pathways for a wider variety of formulation characteristics, such as large-volume or high-viscosity drugs. The NIT unit eliminates the need for patients to manually attach the needle prior to injection.
Aria is a novel reusable electronic autoinjector, designed to meet current and emerging needs of the self-injection market for biopharmaceuticals. It consists of a reusable electronic power unit, coupled with a disposable cassette, which contains either a 1ml or 2.25mL pre-filled syringe and provides needle safety, using a moveable shield, similar to most disposable devices.
The reusable format significantly improves sustainability over conventional disposable autoinjectors and includes built in Bluetooth connectivity. The device provides clear audible and visual feedback throughout the injection process. It is being developed as a device platform for multiple therapies.
YpsoMate 5.5 autoinjector is an automated injection device for 5.5 mL pre-filled glass syringes suitable for all patient groups. The device is triggered by push-on-skin activation which is convenient, ergonomic and preferred by patients.
-Taking handheld self-injection beyond volumes of 2.0 mL
-New ready-to-use 5.5 mL staked-needle pre-filled syringe format
-Market-proven two-step YpsoMate technology
-Bespoke user interface increases confidence during injection
-Easy customisation for a broad range of fill volumes, viscosities and injection times
Owen Mumford Pharmaceutical Services are proud to announce the launch of Aidaptus® a 2-step single-use auto-injector platform.
- Aidaptus® is a 2-step single use auto-injector platform, with a versatile design and intuitive drug delivery.
- Aidaptus® accommodates both 1mL and 2.25mL glass syringes in the same device, and readily adapts to different fill volumes with no changed parts.
- Aidaptus® is suitable for reducing risk during drug development and lifecycle management.
To find out more please visit our website.
Expanding the potential of intradermal injection.Immucise was born from Terumo’s passionate spirit to achieve its mission. The developed needle structure in combination with a vertical injection aims for a simple and precise intradermal injection, to deliver drug to the dermis layer.
Pharmapack is a great place to learn about the latest developments and new ideas from the industry. You can discuss interesting topics, share your experiences and strengthen relationships with your partners.